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1

Real-time monitoring of the membrane-binding and insertion properties of the cholesterol-dependent cytolysin anthrolysin O from Bacillus anthracis

Simon Cocklin, Monika Jost, Noreen M Robertson, Stephen D Weeks, Hans-Walter Weber, Emily Young, Samar Seal, Can Zhang, Elise Mosser, Patrick J Loll, Aleister J Saunders, Richard F Rest, Irwin M Chaik

Journal:

Journal of Molecular Recognition

Year:

2006

Language:

english

File:

PDF, 303 KB

english, 2006

2

A ligand-mediated dimerization mode for vancomycin

Patrick J. Loll, Russ Miller, Charles M. Weeks, Paul H. Axelsen

Journal:

Chemistry & Biology

Year:

1998

Language:

english

File:

PDF, 755 KB

english, 1998

3

Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture

Stephen D. Weeks, Kimberly C. Grasty, Lisa Hernandez-Cuebas, Patrick J. Loll

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 199 KB

english, 2009

4

The crystal structure of the ternary complex of staphylococcal nuclease, Ca2+ and the inhibitor pdTp, refined at 1.65 Å

Patrick J. Loll, Eaton E. Lattman

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1989

Language:

english

File:

PDF, 1.52 MB

english, 1989

5

Strategies for crystallizing membrane proteins

R. Michael Garavito, Daniel Picot, Patrick J. Loll

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1996

Language:

english

File:

PDF, 1.85 MB

english, 1996

6

Strategies for crystallizing membrane proteins

R. Michael Garavito, Daniel Picot, Patrick J. Loll

Journal:

Journal of Bioenergetics and Biomembranes

Year:

1996

Language:

english

File:

PDF, 1.85 MB

english, 1996

7

Manipulation of kinetic profiles in 2-aryl propionic acid cyclooxygenase inhibitors

Kushol Gupta, Carl J. Kaub, Kristen N. Carey, Eduard G. Casillas, Barry S. Selinsky, Patrick J. Loll

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 225 KB

english, 2004

8

The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

Picot, Daniel, Loll, Patrick J., Garavito, R. Michael

Journal:

Year:

1994

File:

PDF, 1.17 MB

1994

9

The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase

Loll, Patrick J., Picot, Daniel, Garavito, R. Michael

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 961 KB

1995

10

A molecular dipstick?

Funk, Colin D., Loll, Patrick J.

Journal:

Natural Structural Biology

Year:

1997

File:

PDF, 445 KB

1997

11

Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein

Mattoon, Dawn, Gupta, Kushol, Doyon, Jeffrey, Loll, Patrick J, DiMaio, Daniel

Journal:

Year:

2001

Language:

english

File:

PDF, 471 KB

english, 2001

12

Static light scattering studies of OmpF porin: Implications for integral membrane protein crystallization

Carl Hitscherich Jr., Margaret Allaman, John Wiencek, Jeffrey Kaplan, Patrick J. Loll

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 230 KB

english, 2000

13

A Carrier Protein Strategy Yields the Structure of Dalbavancin

Economou, Nicoleta J., Nahoum, Virginie, Weeks, Stephen D., Grasty, Kimberly C., Zentner, Isaac J., Townsend, Tracy M., Bhuiya, Mohammad W., Cocklin, Simon, Loll, Patrick J.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 3.46 MB

english, 2012

14

Structural Basis for Calmodulin as a Dynamic Calcium Sensor

Miao Zhang, Cameron Abrams, Liping Wang, Anthony Gizzi, Liping He, Ruihe Lin, Yuan Chen, Patrick J. Loll, John M. Pascal, Ji-fang Zhang

Journal:

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

15

Crystallography Made Crystal Clear: A Guide for Users of Macromolecular Models (2nd edn): Gale Rhodes, Academic Press, New York, 2000, pp. 267. $44.95. ISBN 0-125-87072-2.

Journal:

Biochemistry and Molecular Biology Education

Year:

2000

Language:

english

File:

PDF, 72 KB

english, 2000

16

Structural Analysis of NSAID Binding by Prostaglandin H2 Synthase: Time-Dependent and Time-Independent Inhibitors Elicit Identical Enzyme Conformations†

Selinsky, Barry S., Gupta, Kushol, Sharkey, Caroline T., Loll, Patrick J.

Journal:

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

17

The four-helix bundle: An attractive fold

Roderic G. Eckenhoff, Renyu Liu, Jonas S. Johansson, Patrick J. Loll

Journal:

International Congress Series

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

18

The 2.0 Å Resolution Crystal Structure of Prostaglandin H2 Synthase-1: Structural Insights into an Unusual Peroxidase

Kushol Gupta, Barry S Selinsky, Carl J Kaub, Amy K Katz, Patrick J Loll

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 2.06 MB

english, 2004

19

Vancomycin Forms Ligand-Mediated Supramolecular Complexes

Patrick J. Loll, Ariss Derhovanessian, Maxim V. Shapovalov, Jeffrey Kaplan, Lin Yang, Paul H. Axelsen

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.12 MB

english, 2009

20

Ligation independent cloning vectors for expression of SUMO fusions

Stephen D. Weeks, Mark Drinker, Patrick J. Loll

Journal:

Protein Expression and Purification

Year:

2007

Language:

english

File:

PDF, 538 KB

english, 2007

21

Membrane protein structural biology: the high throughput challenge

Journal:

Journal of Structural Biology

Year:

2003

Language:

english

File:

PDF, 183 KB

english, 2003

22

Colicin Occlusion of OmpF and TolC Channels: Outer Membrane Translocons for Colicin Import

Zakharov, Stanislav D., Eroukova, Veronika Y., Rokitskaya, Tatyana I., Zhalnina, Mariya V., Sharma, Onkar, Loll, Patrick J., Zgurskaya, Helen I., Antonenko, Yuri N., Cramer, William A.

Journal:

Biophysical Journal

Year:

2004

Language:

english

File:

PDF, 478 KB

english, 2004

23

Quartz Crystal Microbalance (QCM): Useful for Developing Procedures for Immobilization of Proteins on Solid Surfaces

Sha, Xue, Sun, Chengjun, Xu, Xiaohe, Alexander, Laura, Loll, Patrick J., Penn, Lynn S.

Journal:

Analytical Chemistry

Year:

2012

Language:

english

File:

PDF, 580 KB

english, 2012

24

X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide

Loll, Patrick J., Quirk, Stephen, Lattman, Eaton E., Garavito, R. Michael

Journal:

Year:

1995

Language:

english

File:

PDF, 995 KB

english, 1995

25

The Role of Sugar Residues in Molecular Recognition by Vancomycin †

Kaplan, Jeffrey, Korty, Brian D., Axelsen, Paul H., Loll, Patrick J.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001

26

The Structural Biology of Molecular Recognition by Vancomycin

Loll, Patrick J., Axelsen, Paul H.

Journal:

Annual Review of Biophysics and Biomolecular Structure

Year:

2000

Language:

english

File:

PDF, 283 KB

english, 2000

27

The Role of Configurational Entropy in Biochemical Cooperativity

Jusuf, Sutjano, Loll, Patrick J., Axelsen, Paul H.

Journal:

Journal of the American Chemical Society

Year:

2002

Language:

english

File:

PDF, 64 KB

english, 2002

28

The high resolution structure of tyrocidine A reveals an amphipathic dimer

Loll, Patrick J., Upton, Elizabeth C., Nahoum, Virginie, Economou, Nicoleta J., Cocklin, Simon

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 1.51 MB

english, 2014

29

Prostaglandin H synthase

Garavito, R.Michael, Picot, Daniel, Loll, Patrick J.

Journal:

Current Opinion in Structural Biology

Year:

1994

Language:

english

File:

PDF, 1.49 MB

english, 1994

30

Crystalization of Biological Macromoleculesby Alexander McPherson

Review by: Patrick J. Loll

Journal:

Quarterly Review of Biology

Year:

2000

Language:

english

File:

PDF, 125 KB

english, 2000

31

Simultaneous Recognition of a Carboxylate-Containing Ligand and an Intramolecular Surrogate Ligand in the Crystal Structure of an Asymmetric Vancomycin Dimer

Loll, Patrick J., Bevivino, Anthony E., Korty, Brian D., Axelsen, Paul H.

Journal:

Journal of the American Chemical Society

Year:

1997

Language:

english

File:

PDF, 212 KB

english, 1997

32

Vancomycin Binding to Low-Affinity Ligands: Delineating a Minimum Set of Interactions Necessary for High-Affinity Binding §

Loll, Patrick J., Kaplan, Jeffrey, Selinsky, Barry S., Axelsen, Paul H.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 85 KB

english, 1999

33

Photoactive Analogues of the Haloether Anesthetics Provide High-Resolution Features from Low-Affinity Interactions

Xi, Jin, Liu, Renyu, Rossi, Matthew J., Yang, Jay, Loll, Patrick J., Dailey, William P., Eckenhoff, Roderic G.

Journal:

ACS Chemical Biology

Year:

2006

Language:

english

File:

PDF, 1.91 MB

english, 2006

34

Configurational Entropy and Cooperativity between Ligand Binding and Dimerization in Glycopeptide Antibiotics

Jusuf, Sutjano, Loll, Patrick J., Axelsen, Paul H.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 128 KB

english, 2003

35

A Protein Engineering Approach Differentiates the Functional Importance of Carbohydrate Moieties of Interleukin-5 Receptor α

Ishino, Tetsuya, Economou, Nicoleta J., McFadden, Karyn, Zaks-Zilberman, Meirav, Jost, Monika, Baxter, Sabine, Contarino, Mark R., Harrington, Adrian E., Loll, Patrick J., Pasut, Gianfranco, Lievens,

Journal:

Year:

2011

Language:

english

File:

PDF, 3.44 MB

english, 2011

36

Assessing Micellar Interaction and Growth in Detergent Solutions Used to Crystallize Integral Membrane Proteins

Loll, Patrick J., Hitscherich,, Carl, Aseyev, Vladimir, Allaman, Margaret, Wiencek, John

Journal:

Crystal Growth & Design

Year:

2002

Language:

english

File:

PDF, 127 KB

english, 2002

37

Synthesis and Use of Iodinated Nonsteroidal Antiinflammatory Drug Analogs as Crystallographic Probes of the Prostaglandin H 2 Synthase Cyclooxygenase Active Site †,‡

Loll, Patrick J., Picot, Daniel, Ekabo, Opinya, Garavito, R. Michael

Journal:

Year:

1996

Language:

english

File:

PDF, 608 KB

english, 1996

38

Active site mutant Glu-43 .fwdarw. Asp in staphylococcal nuclease displays nonlocal structural changes

Loll, Patrick J., Lattman, Eaton Edward

Journal:

Year:

1990

Language:

english

File:

PDF, 886 KB

english, 1990

39

Membrane proteins, detergents and crystals: what is the state of the art?

Loll, Patrick J.

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2014

Language:

english

File:

PDF, 178 KB

english, 2014

40

Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach

Economou, Nicoleta J., Zentner, Isaac J., Lazo, Edwin, Jakoncic, Jean, Stojanoff, Vivian, Weeks, Stephen D., Grasty, Kimberly C., Cocklin, Simon, Loll, Patrick J.

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2013

Language:

english

File:

PDF, 1.74 MB

english, 2013

41

Enhancing ubiquitin crystallization through surface-entropy reduction

Loll, Patrick J., Xu, Peining, Schmidt, John T., Melideo, Scott L.

Journal:

Acta Crystallographica Section F Structural Biology Communications

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

42

First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer

Arturo, Emilia C., Gupta, Kushol, Héroux, Annie, Stith, Linda, Cross, Penelope J., Parker, Emily J., Loll, Patrick J., Jaffe, Eileen K.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

43

Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids

Görner, Christian, Schrepfer, Patrick, Redai, Veronika, Wallrapp, Frank, Loll, Bernhard, Eisenreich, Wolfgang, Haslbeck, Martin, Brück, Thomas

Journal:

Microbial Cell Factories

Year:

2016

Language:

english

File:

PDF, 2.10 MB

english, 2016

44

PRELIMINARY X-RAY INVESTIGATIONS INTO NSAID-BINDING TO CYCLOOXYGENASE-1

Garavito, R. Michael, Picot, Daniel, Loll, Patrick J.

Journal:

American Journal of Therapeutics

Year:

1995

File:

PDF, 384 KB

1995

45

Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac

Kinde, Monica N., Bondarenko, Vasyl, Granata, Daniele, Bu, Weiming, Grasty, Kimberly C., Loll, Patrick J., Carnevale, Vincenzo, Klein, Michael L., Eckenhoff, Roderic G., Tang, Pei, Xu, Yan

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.24 MB

english, 2016

46

Evidence that three-regime kinetics is inherent to formation of a polymer brush by a grafting-to approach

Sha, Xue, Xu, Xiaohe, Sohlberg, Karl, Loll, Patrick J., Penn, Lynn S.

Journal:

Year:

2014

Language:

english

File:

PDF, 609 KB

english, 2014

47

Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels

Bu, Weiming, Liang, Qiansheng, Zhi, Lianteng, Maciunas, Lina, Loll, Patrick J., Eckenhoff, Roderic G., Covarrubias, Manuel

Journal:

Molecular Neurobiology

Year:

2017

Language:

english

File:

PDF, 2.18 MB

english, 2017

48

Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation

Woll, Kellie A., Peng, Wesley, Liang, Qiansheng, Zhi, Lianteng, Jacobs, Jack A., Maciunas, Lina, Bhanu, Natarajan, Garcia, Benjamin A., Covarrubias, Manuel, Loll, Patrick J., Dailey, William P., Ecken

Journal:

ACS Chemical Biology

Year:

2017

Language:

english

File:

PDF, 1.83 MB

english, 2017

49

Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding

Rao, Maya V., Williams, Dewight R., Cocklin, Simon, Loll, Patrick J.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 8.09 MB

english, 2017

50

[Methods in Enzymology] || Structural Analysis of Anesthetics in Complex With Soluble Proteins

Loll, Patrick J.

Year:

2018

Language:

english

File:

PDF, 591 KB

english, 2018